Microarray and Genomics Core

The DNA Microarray and Genomics Facility will afford RPCI investigators a full spectrum of services for parallel analyses of genomes and their expression. Applications of this technology include Comparative Genomic Hybridization (CGH), and global gene expression profiling. Variations of these applications can be utilized to: detect and map chromosomal aberrations, profile gene expression patterns in tumors, identifying differences between two populations of DNA or RNA (ie. transfected vs. untransfected cell populations), determine the effect of therapeutic agents on gene expression, and determine the effect of genetic alterations on gene expression patterns in transgenic and knockout mice. The facility also maintains and provides a screening and clone characterization service for nine large insert genomic BAC & PAC libraries for human, mouse, rat, and S. Pombe as a resource for RPCI investigators.

URL: http://microarrays.roswellpark.org

Location:
Microarray and Genomics Core Facility
Roswell Park Cancer Institute
Elm and Carlton Streets
Buffalo, NY 14263

Director:
Norma J. Nowak, Ph.D.
Director, Microarray and Genomics
T: [716] 845-8966
F: [716] 845-1579
E: Norma.nowak@roswellpark.org

Jeffrey M. Conroy
Co-Director, Microarray and Genomics
T: [716] 845-3361
F: [716] 845-1579