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Kang Sun Lee

  • Graduate Research Assistant

  • SMALL (nanobio Sensors and MicroActuators Lab)
    Department of Electrical Engineering
    Bonner Hall #326
    University at Buffalo, The State University of New York (SUNY at Buffalo)
    Buffalo, NY 14260

    Tel: (716) 645-3115
    Fax: (716) 645-3656

  • E-mail: kl63@buffao.edu, kslee1230@gmail.com

  • Web-site: www.SMALL.buffalo.edu
Research at SMALL

  • Serial dilution based microfluidics

  • SMALL member since Spring 2008
Objective

  • Pursuing a challenging career in research and development of bio-MEMS, NEMS and microsystem

Education - Ph.D. (January 2008 – current)

  • University at Buffalo, The State University of New York (SUNY at Buffalo)

  • Department of Electrical Engineering

  • Advisor: Dr. Kwang W. Oh
Education - M.S. (March 2004 – February 2006)

  • Dankook University, Seoul, KOREA

  • Electrical Engineering

  • Thesis topic: Fabrication of LOC system for cell manipulation with a micro fluid mixer and a cell separator

  • Advisors: Prof. Seung-Ki Lee (Dankook University) and Dr. Ji Yoon Kang (KIST)
Education - B.S. ( – February 2004)

  • Dankook University, Seoul, KOREA

  • Electronic and Computer Engineering

  • Related Courses

    • MEMS, Bio-MEMS, Optical electronics, Semiconductor Technology, Electronic circuits Thin film technology, Signal process, System Control, Essential biology, Molecular cell biology, Microfluidics

Research Experience

  • Research Scientist, Nano-Bio System Laboratory, Microsystem Research Center, Korea Institute of Science and Technology (03/2006 -12/2007)

    • Development of a multi cell sorter using hydrogel (alginate) capsules

    • Development of a dilution chip for cell culture

    • Development of a hydrodynamic device for capsules trap

    • Work resulted in 2 patents (preparation: 2) and 1 presentation

  • Graduate Research Assistant, Nano-Bio System Laboratory, Microsystem Research Center, Korea Institute of Science and Technology (03/2005 - 02/2006)

    • Fabrication of 3D serpentine micro mixer using surface tension of PDMS

    • Development of droplet based MACS Portable for a commercial

    • Fabrication of LOC system for cell manipulation with a micro fluid mixer and a cell separator

    • Work resulted in 1 patent, 2 presentations and 3 papers (preparation: 3)

  • Graduate Research Assistant, DIANA Laboratory, Microsystem Research Center, Korea Institute of Science and Technology (03/2004 - 02/2005)

    • Fabrication of cell sorter using dielectrophoresis

    • Development of droplet based MACS (Magnetically Activated Cell Separator) system

    • Development of the fabrication method of microchannel with a round cross section
      using surface tension of PDMS

    • Work resulted in 2 patents, 2 presentations

  • Internship, Micro-Robot Laboratory, Microsystem Research Center, Korea Institute of Science and Technology (08/2003 - 02/2004)

    • Fabrication of cell manipulator using conducting polymer micro actuators and dielectrophoresis electrode
Skills

  • Fabrication and Metrology Equipment: MA6 mask aligners, Spinners, RIE, PECVD, E-beam evaporator, Sputter, ¥á-Step, Confocal, AFM

  • Programming and Engineering Packages: Matlab, CFD-RC

  • Graphic tools: Auto CAD, Solid works, 3D-MAX
Membership/ Activities

  • Member of the soccer club (DACS) in Dankook University (March 1997 - February 2004)
Award/Fellowships

  • Research assistantship in 2008

  • Research fund granted by a government for Post-master.

  • Scholarship in August 2005

  • Research assistantship in March 2005

  • Research assistantship in August 2004

Publications - Journals

  • Choong Kim, Kangsun Lee, Kyeong-Sik Shin, Kyujung Lee, Tae Song Kim and Ji Yoon Kang, ¡°A serial dilution microfluidic device using ladder network generating logarithmic or linear concentrations¡±, Lab on a Chip, 8, 473–479 (2008)

  • Kangsun Lee, Choong Kim, Jin Woo Lee, Byeong Kwon Ju, Tae Song Kim, Seung-Ki Lee and Ji Yoon Kang, ¡°Fabrication of Round Channel Using Surface Tension of PDMS and its Application to a 3D Serpentine Mixer¡±, J. Micromech. Microeng., 17, 1533-154 (2007)

  • Youngho Kim, Su-Hong, Sang-Ho Lee, Kangsun Lee, Seok Yun, Yuri Kang, Kyeong-Kap Paek, Byeong-Kwon Ju, Byung-Kyu Kim, ¡°Novel platform for minimizing cell loss on separation process: Droplet-based magnetically activated cell separator¡±, Review of Scientific Instruments, 78, 074301-1-7 (2007)

  • Choong Kim, In Hye Lee, Kangsun Lee, Sung Shin Ryu, Sangho Lee, KyuJung Lee, Jinwoo Lee, Ji Yoon Kang, and Tae Song Kim, ¡°Rapid and Uniform Formation of Embryoid Body of Mouse ES Cells in EBAC (embryonic body array chip)¡±, Bioscience, Biotechnology, and Biochemistry, to be published (2007)

  • Kangsun Lee, Choong Kim, Sung Shin Ryu, In Hye Lee, Byeong Kwon Ju, Seung-Ki Lee and Ji Yoon Kang, ¡°Droplet Based Immunomagnetic Cell Separator¡±, Biochip journal (2007)
Publications - Conferences/Workshops

  • Kangsun Lee, Choong Kim, Jung-Rak Lee, Tae Song Kim and Ji Yoon Kang, ¡°Fabrication and Characterization of Magnetic Alginate Bead Carriers for Multiple Sorting of Cells or Multiplexed Immunoassay¡±, The 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences (Micro TAS 2007), Paris, France, October 7-11 (2007)

  • Choong Kim, Kangsun Lee, Kyungsik Shin, Jong-Hyun Kim, Kyu-Jung Lee, Ji Yoon Kang and Tae Song Kim, ¡°Serial dilution chips for arbitrary concentration profile and application for cytotoxycity test¡±, The 11th International Conference on
    Miniaturized Systems for Chemistry and Life Sciences (Micro TAS 2007), Paris, France, October 7-11 (2007)

  • Choong Kim, Kangsun Lee, In-Hye Lee, Kyungsik Shin, Edward Kang, Kyu-Jung Lee and Ji Yoon Kang ¡°Three dimensional perfusion culture of encapsulated embryonic stem cells in microfluidic chip¡±, The 14th international Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 07), Lyon, France, June 10-14 (2007)

  • Choong Kim, Kang Sun Lee, Sung Shin Ryu, Kyung Sik Shin, Kyu Jung Lee, Ji Yoon Kang and Tae Song Kim, ¡°The serial dilution chip for cytotoxycity and cell differenciation test II¡±, The 20th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2007), Kobe, Japan, January 21-25 (2007)

  • Choong Kim, Kang Sun Lee, Sung Shin Ryu, Kyung Sik Shin, Kyu Jung Lee, Ji Yoon Kang and Tae Song Kim, ¡°The serial dilution chip for cytotoxycity and cell differenciation test¡±, Micro Total Analysis System 2006, Tokyo, Japan, November 5-9 (2006)

  • Kang Sun Lee, Choong Kim, Youngho Kim, Jinwoo Lee, Myung-Hwan Oh, Byeongkwon Ju, and Seung-Ki Lee, ¡°Fabrication method of Rounded-shaped cross sectional channel using a difference between adsorption and cohesion of PDMS¡±, The 13th international Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 05), Seoul, Korea, July 5-9 (2005)

  • Kangsun Lee, Choong Kim, Jung-Rak Lee, Jong-Hyun Kim, Tae Song Kim and Ji Yoon Kang, ¡°Fabrication and characterization of magnetic bead capsules for multiple cell sorting¡±, The 9th Korean MEMS conference, Jeju, Korea, April 6-7 (2007)

  • Choong Kim, Kangsun Lee, Jong-Hyun Kim, Kyu-Jung Lee, Tae song Kim and Ji Yoon Kang, ¡°Microencapsulation and embryonic body formation of embryonic stem cells using two-phase microfluidic chip¡±, The 9th Korean MEMS conference 2007, Jeju, Korea, April 6-7 (2007)

  • Kangsun Lee, Choong Kim, Sung Shin Ryu, Ji Yoon Kang, Byung Kwon Ju and Seung-Ki Lee, ¡°Fabrication of a micro mixer using surface tension and the application for a cell separator¡±, The 8th Korean MEMS conference 2006, Jeju, Korea, April 5-6 (2006)

  • Kang Sun Lee, Choong Kim, Jin Woo Lee, Ji Yoon Kang, Myung Hwan Oh, Byung Kwon Ju, Seung-Ki Lee, ¡°Characterization of rounded cross-section microchannels fabricated by using of surface tension¡±, International Sensors Conference, Taejon, November 11-12 (2005)

  • Kang Sun Lee, Youngho Kim, Seok Yoon, Yu Ri Kang, Dae Seok Na, Jin Woo Lee, Kyung Kwap Beak, Myung Hwan Oh,Byung Kwon Ju and Seung-Ki Lee, ¡°Fabrication method of round-shaped microchannel using surface tension of PDMS¡±, The International Sensors Conference, Jeju, November (2004)

  • Jung-ryul Park, Seok Yun, Kang Sun Lee, Byunkyu Kim, Byunkwon Ju and Kyo-Il Lee, ¡°Design and analysis of Dielectrophoretically Activated Cell Sorting system using 3D-Asymmetric Microelectrodes¡±, The 6th Korean MEMS Conference, Jeju, April 8-10 (2004)
Patents

  • Kangsun Lee, Sung Shin Ryu In Hye Lee, Choong Kim and Ji Yoon Kang, ¡° Apparatus and method for separating biological particles using difference between gravity and magnetic force¡±, PCT/KR2007/197 (2007)

  • Ji Yoon Kang, Choong Kim, Kangsun Lee, Sung-Shin Ryu, Tae Song Kim ¡°A chip having microchannels and a method for continuous dilution of solution¡±, Korea, 2007-0035440 (2007)

  • Kang Sun Lee, Sung Shin Ryu, In Hye Lee, Choong Kim, Su Kyung Chae, Jin Woo Lee and Ji Yoon Kang, ¡°Apparatus and method for separating biological particles using difference between gravity and magnetic force¡±, Korea, 2006-0003260 (2006)

  • Choong Kim, Su Kyung Chae, Kang Sun Lee, In Hye Lee, Jin Woo Lee, Ji Yoon Kang and Tae Song Kim, ¡°Method and apparatus for forming and growing embryonic body¡±, Korea, 2006-0003249 (2006)

  • Kang Sun Lee, Choong Kim, Su Kyung Chae, Jin Woo Lee, Tae Song Kim, Ji Yoon Kang, Byung Kwon Ju, Seung-Ki Lee, ¡°A method of fabricating microchannel using surface tension and the microchannel¡±, Korea, 2005-32696 (2005)

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