CURRENT EXTERNAL FUNDING

 

The primary mission of the Center for Hearing and Deafness is to conduct research. This mission is funded in

large part by grants and contracts from government and private sources, as well as through support from the

university.

 

The Center is available to execute contracts for specific research projects, to serve as a training and research

facility for personnel from industry, and to provide consultants for legal matters pertaining to hearing loss.

 

The Center actively collaborates with clinicians, scientists, and researchers from other institutions in the U.S.

and abroad. These affiliated scientists provide a unique and important resource, bringing new skills and ideas

to the laboratory and expanding the scope of the research programs. Collaborations, which range from sharing

projects to hosting international symposia, have been undertaken with visitors from China, France, Italy, India,

and Japan, as well as other centers in the U.S.

 

 

P.I.

Sponsor

Project Title/Focus of Project

Funding Period

Dalian Ding

NIH / Jackson Labs

 
Genetics of Age-Related Hearing Loss; This project is 
aimed at identifying genes and their modifiers that cause 
age-related hearing loss.

12/01/06 to 11/30/10

Donald Henderson

NIOSH

Prevention of Solvent and Noise-Induced Hearing Loss; The focus of this grant is on chemically-induced hearing loss, the mechanism of solvent-induced hair cell loss, and the exploration of possible protection strategies.

05/01/05 - 04/30/10
Samson Jamesdaniel NIDCD Role of Protein Nitration in Cisplatin Mediated Ototoxicity; This project investigates the nitration of cochlear proteins, which is considered as an oxidative posttranslational modification that can lead to catastrophic consequences. Determination of cisplatin-induced nitration of cochlear proteins and its correlation with hearing loss, Identification of the nitrated cochlear proteins and evaluation of the role of protein nitration in cisplatin mediated ototoxicity, using inhibitors, are some of the important aims of this study.

07/01/09 – 06/30/12
Edward Lobarinas Tinnitus Res. Initiative

Pharmacological Workgroup; supports an international research group that is currently evaluating tinnitus drug therapies in humans and animals. The current work will focus on evaluating the effects of new drugs on noise induced tinnitus in animals.

09/29/08 to 09/28/10

Richard Salvi

NIH

Effect of Inner Hair Cell Loss on Auditory Function; The goal of this project is to identify the effect that selective IHC loss has on auditory perceptual measures in the chinchilla, to measure the physiological changes that occur in the central auditory system and to correlate the physiological and behavioral measures.

05/01/04 to 10/30/09

Richard Salvi

NIDCD

Animal Models of Tinnitus, Brain Imaging & Therapy; The goal of this project is to identify the neural correlates of tinnitus in the auditory cortex using animal models with behavioral evidence of tinnitus, image brain metabolic function associated with tinnitus, and assess therapeutic compounds that may suppress tinnitus.

09/01/07 to 08/31/12

Richard Salvi

American Tinnitus Assoc.

 
Changes in the Ensemble of Spontaneous Activity
in Awake Animals with Tinnitus;The goal of this
ATA student grant is to investigate changes in 
oscillatory activity in the auditory cortex of awake rats
experiencing tinnitus.

01/01/08 to 12/31/08

Richard Salvi

NIDCD

Neural Aspects of Tinnitus; The primary goals of this project are to evaluate the physiological changes that occur in the auditory cortex in animal models that can report on the presence of tinnitus and to evaluate two different drug therapies to suppress tinnitus.

03/01/08 to 02/28/13
Richard Salvi Tinnitus Res. Initiative Neurostimulation Workshop; This project will assess the local field potentials and multiunit activity in the auditory cortex of awake rates during salicylate induced tinnitus, noise induced tinnitus and assess the effects of transcranial magnetic stimulation on these activity patterns.

09/29/08 to 09/28/10

Wei Sun

NIH

Mechanism of Auditory Cortex Development and Role of NMDA Receptors; The major goals of this project are to study the auditory cortex develop-mental change and the role of NMDA receptors.

12/01/06 to 11/30/09
Wei Sun Am. Federation for Aging Research

How Presbycusis Affects Tinnitus; The goal of this grant is to find whether the central auditory reorganization induced by the presbycusis is related to tinnitus generation. 

10/01/08 to 09/30/10
Wei Sun Royal National Inst. For Deaf People

Auditory Cortex Reorganization Related to Tinnitus and Hyperacusis; The goal of this grant is to study how central reorganization is related to tinnitus and hyperacusis.  We will use tinnitus animal model induced by salicylate and noise exposure in this project.

10/01/08 to 09/30/11
Mei Zhang NIDCD Role of P53 in Aminoglycoside Otoxocity; The goal of the study is to understand the mechanisms of PFT protective effect against hair cell death.

02/01/08 to 01/31/10