Fall 2003 Term
Department of Psychology
State University of New York at Buffalo
Michael A. Bozarth, Ph.D.
B-77 Park Hall, North Campus
Office Hours: Wednesday 1:15-3:00 p.m.
plus most T/R 3:30 - 6:00 p.m.
Telephone: 645-3650 ext. 677
Online Course Material
|Dose-Response Analysis (efficacy vs. potency)||Classification of Agonists & Antagonists|
|Tolerance & Sensitization||Additive Effects, Synergism & Potentiation|
|Drug Classification||Clinical Psychopharmacology|
This course surveys basic neuropharmacology, the effects of various psychotropic drugs, and the actions of drugs used to treat mental disorders. The emphasis of the first part of the course is on basic principles of neuropharmacology, distribution and elimination of drugs, drug-receptor interactions and dose-response relationships, structure of neurons, neurophysiological mechanisms involved in synaptic activity, and the distribution of specific neurotransmitter systems. The last two-thirds of the course examines the actions of specific drugs and their effects on behavior and their uses in biological psychiatry. This course is designed to provide a foundation for advanced study in behavioral neuroscience, neuropsychopharmacology, physiological psychology, and related areas and to provide an introduction to the pharmacological treatment of mental disorders for clinical students. The course also provides part of the requisite training for prescribing privileges currently awarded clinical psychologists in some states.
Introductory Psychology, Research Methods or equivalent, Biopsychology or Behavioral Neuroscience; or by permission of instructor. A background in biological sciences is strongly recommended. Highly motivated students lacking the formal course prerequisites should contact the instructor prior to enrollment.
This is a lecture course with student presentations and limited group
discussions. Reading assignments from the textbook and from supplementary
readings are an important part of this course. Video recordings and laboratory
demonstrations may be used to enhance the presentation of some material.
Some material will be available only on the Internet and students are required
to have an active computer account. An Internet-based discussion group
will also be used to address questions regarding the reading assignments
and the lecture material.
|Changing classroom dynamics necessitate posting some explicit expectations for student behavior. Click here to read principles of student conduct in effect for this course that supplement those outlined in the University at Buffalo Undergraduate Catalog. Continued enrollment in this course presumes the student has read and will adhere to these principles.|
A Primer on Drug Action, Ninth Edition (Julien, 2000) is the required text for this course. Supplementary readings will be assigned when appropriate. Students should be prepared for a heavy reading load throughout the semester.
Grades are determined by performance on three equally weighted examinations
(25% each), unannounced 'pop' quizzes (15%), and class presentation material
(10%). The three term exams will be scheduled during regular class periods
and should require about an hour to complete. The 'pop' quizzes will be
given during the beginning of some classes throughout the term and should
require 15 to 20 minutes to complete; the lowest two quiz grades will be
dropped from the grade calculations (this includes any missed quizzes).
The test format may vary using any combination of multiple choice, short
answer, and essay questions. Quizzes cannot be made up, and makeup
exams are allowed only with permission of the instructor prior to the scheduled
test date. Extraordinary circumstances, along with the appropriate
documentation, should be brought to the attention of the instructor for
|25% each (three exams)
The material contained on this web site and the material presented in class are protected by Federal copyright laws. Students are expressly prohibited from compilation and distribution of class material except for their own private use.
Tentative Course Outline
Brief Overview of Fundamental Disciplines
Basic Principles of PharmacologymorphologyNeurophysiology
physiology & cell metabolismcell potentialsNeurochemistry
electrophysiological techniquessynaptic transmissionNeuroanatomy
signal transductioncentral nervous system (CNS)
peripheral nervous system (PNS)
Pharmacokineticsdrug absorption & distributionPharmacodynamics
drug eliminationreceptor binding
|25 September||Exam #1||Exam Scores|
|30 September||Review & Presentation Guide
|Date||Topic||Reading Assignment||Online Material|
|02 October||Group Meeting Day|
|07 October||Ethyl Alcohol & Abused Inhalants||Chapter 4||student outline|
|09 October||Barbiturates, General Anesthetics, & Antiepileptic Drugs||Chapter 5||student outline|
|14 October||Benzodiazepines & Second-Generation Anxiolytics||Chapter 6||presentation
|16 October||Psychomotor Stimulants||Chapter 7||student outline|
|21 October||Opioids & Other Analgesics||Chapters 9 & 10||student outline|
|23 October||Module Overview||Special Notes for Exam #2|
|28 October||Exam #2||Exam Scores|
|30 October||Review & Group Work|
|04 November||Drugs Used to Treat Depression||Chapter 15||student outline|
|06 November||Drugs Used to Treat Bipolar Disorder||Chapter 16||student outline|
|11 November||Drugs Used to Treat Schizophrenia||Chapter 17||student outline|
|13 November||Drugs Used to Treat Parkinsonism||Chapter 18||student outline|
|18 November||Clinical Psychopharmacology:
Issues and Answers
|20 November||Module Overview||Special Notes for Exam #3|
|25 November||(optional) Graduate School & Careers in Psychopharmacology|
|27 November||Class Canceled: Fall Recess|
|02 December||Exam #3||Exam Scores|
|04 December||Review/Course Overview|