The School of Public Health and Health Professions' Population Health Observatory (PHO) at the University at Buffalo is a public health research, training, and informatics center. Our mission is to facilitate the protection and improvement of public health by generating knowledge from data. Local, statewide, national, and international databases provide the foundation for our population-based research. PHO reports are disseminated to the public through this web site, directly to public health professionals and policy makers, and through publication in the research literature. PHO faculty and students engage in health research and associated methodological development. A HIPAA and FERPA compliant public health informatics data warehouse and data management system is at the core of PHO activities.