Toxicology Research Center facilities are equipped to provide
evaluation of antimicrobial activity on a wide variety of materials and surfaces using a variety of test microbes. The Center also possesses the capability to evaluate the effects of the agent on the function of the treated
material.
Evaluation of an antimicrobial treated additive developed and patented by the Center has been conducted using a modified EPA and ASTM methods (EPA 600/8-78-017 & ASTM D5209-92) and organisms from sewage sludge as
well as pure strains (e.g. Pseudomonas).
Materials treated with the additive include HEPA filtration materials that were evaluated for antimicrobial effectiveness using AATCC Methods (AATCC 100-1993) and for
treatment effect on the filtration capacity using ASTM Method F778-88.
Antimicrobial loading and leachability studies of the additive are conducted using thermogravimetric analysis with a microwave ashing system and
employing radiolabelled antimicrobial agent and can also be conducted using GC/Mass Spec or LC methodology.
These materials and methods were developed and modified here at the Center to allow materials analysis and
demonstrate the flexibility and wide range of capabilities of the Centers analytical laboratory. Other microbial work is described under the Biodegradation section.
Patented Antimicrobial Technology